Colgate Total® toothpaste With Triclosan:
The #1 Trusted Choice of Dental Professionals


Colgate Total® has been the trusted choice for healthy teeth and gums for more than 15 years. It’s the brand used and recommended most by dentists and hygienists.

Colgate Total® toothpaste is uniquely formulated with 0.3% of the antibacterial ingredient triclosan to fight harmful plaque germs, which are the cause of most common oral health problems.

There are more published, peer-reviewed clinical studies of Colgate Total® than of any other toothpaste in the world. The efficacy and safety of Colgate Total® is supported by more than 90 clinical studies, involving over 20,000 people, and a broad set of safety evaluations. Our research has been shared with regulatory agencies around the world who have accepted triclosan’s safe and effective use in toothpaste.

Colgate Total® is clinically proven to work better than other toothpastes in reducing the germs that can cause gum disease. It is clinically proven to provide 12-hour protection against plaque germs that can lead to gingivitis, an early form of gum disease. Over 75% of American adults suffer from gingivitis. Plaque and gingivitis, if unchecked, can progress to periodontitis, a more serious and damaging stage of infection that can result in tooth and bone loss. According to the Centers for Disease Control and Prevention, almost half of American adults age 30 and over have serious periodontal disease.

Brushing with regular fluoride toothpaste does not provide the antibacterial protection of Colgate Total® toothpaste. On the US FDA’s website, updated as of September 2, 2016, the FDA states as follows regarding Colgate Total® toothpaste: "For some consumer products, there is evidence that triclosan provides a benefit." The FDA notes that it has “reviewed extensive effectiveness data on triclosan in Colgate Total toothpaste" and that the "evidence showed that triclosan in that product was effective in preventing gingivitis."

Additionally, only Colgate Total® toothpaste provides both antibacterial protection and direct anti-inflammatory action, which is notable given the importance of good oral health and the emerging scientific research associating oral health with overall health.

A thorough independent review was conducted and published by the Cochrane Oral Health Group on the oral health benefits of triclosan/copolymer, the active antibacterial system in Colgate Total® toothpaste. The Cochrane Review evaluated 30 studies dating from 1990 to 2012 and involving 14,835 participants (Riley & Lamont 2013). The resulting data highlighted the many clinical benefits of using a fluoride toothpaste containing triclosan/copolymer and concluded there was no evidence of any harmful effects associated with the use of triclosan/copolymer toothpastes in studies up to three years in duration. Among other things, the Cochrane Review found that after six or more months of use, fluoride toothpaste containing triclosan/copolymer provided:

  • 22% reduction in plaque and gingivitis as compared with traditional fluoride toothpaste

  • 41% reduction in plaque severity as compared with traditional fluoride toothpaste

  • 48% reduction in gum bleeding as compared with traditional fluoride toothpaste

View the full text of the Cochrane Review

More questions about Colgate Total®? Ask Here

Learn More About Colgate’s Ingredient Safety Policy links